Serafin, B., Kamen, A., De Crescenzo, G., & Henry, O. (2025). Impact of Lectin Biotinylation for surface plasmon resonance and enzyme-linked Lectin assays for protein glycosylation. Analytical Biochemistry, 696, 115693 (9 pages).
Directory of Experts
Henry, Olivier
Directory of Experts
Henry, Olivier
Directory of Experts
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Journal article (52)
Conference paper (17)
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Olivier Henry (73)
- 2025 (3)
Journal article Journal article Reyes, S.-J., Lemire, L., Durocher, Y., Voyer, R., Henry, O., & Pham, P. L. (2025). Investigating the metabolic load of monoclonal antibody production conveyed to an inducible CHO cell line using a Transfer-Rate Online Monitoring system. Journal of Biotechnology, 36 pages.Journal article Lemire, L., Reyes Davila, J. S., Durocher, Y., Voyer, R., Henry, O., & Pham, P. L. (2025). N‐1 semi‐continuous transient perfusion in shake flask for ultra‐high density seeding of CHO cell cultures in benchtop bioreactors. Biotechnology Progress, e70029 (14 pages).
- 2024 (6)
Book chapter Forest-Nault, C., Koyuturk, I., Gaudreault, J., Pelletier, A., L'Abbé, D., Cass, B., Bisson, L., Burlacu, A., Delafosse, L., Stuible, M., Henry, O., De Crescenzo, G., & Durocher, Y. (2024). A Biosensor Assay Based on Coiled-Coil-Mediated Human ACE2 Receptor Capture for the Analysis of Its Interactions with the SARS-CoV-2 Receptor Binding Domain. In Bradfute, S. B. (ed.), Recombinant Glycoproteins: Methods and Protocols (pp. 89-105).Journal article Gaudreault, J., Forest-Nault, C., Gilbert, M., Durocher, Y., Henry, O., & De Crescenzo, G. (2024). A low‐temperature SPR‐based assay for monoclonal antibody galactosylation and fucosylation assessment using FcγRIIA/B. Biotechnology and Bioengineering, 121(5), 1659-1673.Journal article Serafin, B., Kamen, A., De Crescenzo, G., & Henry, O. (2024). Antibody-independent surface plasmon resonance assays for influenza vaccine quality control. Applied Microbiology and Biotechnology, 108(1), 307 (10 pages).Journal article Reyes, S.-J., Pham, P. L., Durocher, Y., & Henry, O. (2024). CHO stable pool fed-batch process development of SARS-CoV-2 spike protein production: Impact of aeration conditionsand feeding strategies. Biotechnology Progress, 3507 (20 pages).Journal article Silva, C. A. T., Kamen, A., & Henry, O. (2024). Fed-batch strategies for intensified rVSV vector production in high cell density cultures of suspension HEK293 cells. Biotechnology Progress, 3506 (9 pages).Journal article Reyes, S.-J., Lemire, L., Roy, M., L'Écuyer-Coelho, H., Martynova, Y., Cass, B., Voyer, R., Durocher, Y., Henry, O., Pham, P. L., & Molina, R.-S. (2024). Multivariate data analysis of process parameters affecting the growth and productivity of stable Chinese hamster ovary cell pools expressing SARS‐CoV‐2 spike protein as vaccine antigen in early process development. Biotechnology Progress, e3467 (19 pages).
- 2023 (4)
Conference paper Reyes Davila, J. S., Pham, P. L., Durocher, Y., & Henry, O. (2023, April). CHO stable pool fed-batch process development of SARS-CoV-2 spike protein production [Poster]. Cell Culture Engineering XVIII, Cancun, Mexico (1 page).Journal article Dégardin, M., Liberelle, B., Oliverio, R., Baniahmad, S. F., Darviot, C., Largillière, I., Henry, O., Durocher, Y., Banquy, X., Meunier, M., & De Crescenzo, G. (2023). Coiled-coil-based biofunctionalization of 100 nm gold nanoparticles with the trastuzumab antibody for the detection of HER2-positive cancer cells. Langmuir, 39(34), 12235-12247.Conference paper Silva, C. A. T., Kamen, A. A., & Henry, O. Intensified Influenza Virus Production in Suspension HEK293SF Cell Cultures Operated in Fed-Batch or Perfusion with Continuous Harvest [Paper]. Unspecified (19 pages).Conference paper Silva, C. A. T., Kamen, A. A., & Henry, O. (2023, April). Intensified virus production in suspension HEK293SF cells using high inoculum fed-batch or low-perfusion rate cultures with continuous harvest [Poster]. Cell Culture Engineering XVIII, Cancun, Mexico.
- 2022 (5)
Journal article Forest-Nault, C., Koyuturk, I., Gaudreault, J., Pelletier, A., L'Abbé, D., Cass, B., Bisson, L., Burlacu, A., Delafosse, L., Stuible, M., Henry, O., De Crescenzo, G., & Durocher, Y. (2022). Impact of the temperature on the interactions between common variants of the SARS-CoV-2 receptor binding domain and the human ACE2. Scientific Reports, 12(1), 11520 (11 pages).Conference paper Silva, C. A. T., Kamen, A. A., & Henry, O. (2022, June). Intensification of influenza virus production in fed-batch and perfusion cultures of HEK293SF cells [Paper]. Vaccine Technology VIII, Stiges, Spain.Journal article Yang, Z., Xu, X., Silva, C. A. T., Farnós, O., Venereo-Sánchez, A., Toussaint, C., Dash, S., Gonzalez-Dominguez, I., Bernier, A., Henry, O., & Kamen, A. (2022). Membrane chromatography-based downstream processing for cell-culture produced influenza vaccines. Vaccines, 10(8), 1310 (13 pages).Journal article Reyes, S. J., Durocher, Y., Pham, P. L., & Henry, O. (2022). Modern Sensor Tools and Techniques for Monitoring, Controlling, and Improving Cell Culture Processes. Processes, 10(2), 189 (36 pages).Journal article Gaudreault, J., Durocher, Y., Henry, O., & De Crescenzo, G. (2022). Multi-temperature experiments to ease analysis of heterogeneous binder solutions by surface plasmon resonance biosensing. Scientific Reports, 12(1), 14401 (25 pages).
- 2021 (5)
Journal article Gaudreault, J., Liberelle, B., Durocher, Y., Henry, O., & De Crescenzo, G. (2021). Determination of the composition of heterogeneous binder solutions by surface plasmon resonance biosensing. Scientific Reports, 11(1), 3685 (16 pages).Journal article Gaudreault, J., Forest-Nault, C., De Crescenzo, G., Durocher, Y., & Henry, O. (2021). On the Use of Surface Plasmon Resonance-Based Biosensors for Advanced Bioprocess Monitoring. Processes, 9(11), 1996 (28 pages).Journal article Forest-Nault, C., Gaudreault, J., Henry, O., Durocher, Y., & De Crescenzo, G. (2021). On the use of surface plasmon resonance biosensing to understand IgG-FcγR interactions. International Journal of Molecular Sciences, 22(12), 6616 (27 pages).Book chapter Lemire, L., Pham, P. L., Durocher, Y., & Henry, O. (2021). Practical Considerations for the Scale-Up of Chinese Hamster Ovary (CHO) Cell Cultures. In Cell Culture Engineering and Technology: In appreciation to Professor Mohamed Al-Rubeai (Vol. 10, pp. 367-400).Journal article Silva, C. A. T., Kamen, A. A., & Henry, O. (2021). Recent advances and current challenges in process intensification of cell culture-based influenza virus vaccine manufacturing. Canadian Journal of Chemical Engineering, 99(11), 2525-2535.
- 2020 (3)
Journal article Cambay, F., Forest-Nault, C., Dumoulin, L., Séguin, A., Henry, O., Durocher, Y., & De Crescenzo, G. (2020). Glycosylation of Fcγ receptors influences their interaction with various IgG1 glycoforms. Molecular Immunology, 121, 144-158.Journal article Cambay, F., Raymond, C., Brochu, D., Gilbert, M., Tu, T. M., Cantin, C., Lenferink, A., Grail, M., Henry, O., De Crescenzo, G., & Durocher, Y. (2020). Impact of IgG1 N-glycosylation on their interaction with Fc gamma receptors. Current Research in Immunology, 1, 23-37.Book chapter Henry, O., Karengera, E., Cambay, F., & De Crescenzo, G. (2020). Surface Plasmon Resonance-Based Method for Rapid Product Sialylation Assessment in Cell Culture. In Pörtner, R. (ed.), Animal Cell Biotechnology: Methods and Protocols (Vol. 2095, pp. 285-293).
- 2019 (5)
Journal article Mellahi, K., Brochu, D., Gilbert, M., Perrier, M., Ansorge, S., Durocher, Y., & Henry, O. (2019). Assessment of fed-batch cultivation strategies for an inducible CHO cell line. Journal of Biotechnology, 298, 45-56.Journal article Venereo-Sanchez, A., Fulton, K., Koczka, K., Twine, S., Chahal, P., Ansorge, S., Gilbert, R., Henry, O., & Kamen, A. (2019). Characterization of influenza H1N1 Gag virus-like particles and extracellular vesicles co-produced in HEK-293SF. Vaccine, 37(47), 7100-7107.Journal article Cambay, F., Henry, O., Durocher, Y., & De Crescenzo, G. (2019). Impact of N-glycosylation on Fcγ receptor / IgG interactions: unravelling differences with an enhanced surface plasmon resonance biosensor assay based on coiled-coil interactions. mAbs, 11(3), 435-452.Journal article Mellahi, K., Cambay, F., Brochu, D., Gilbert, M., Perrier, M., Ansorge, S., Durocher, Y., & Henry, O. (2019). Process development for an inducible rituximab-expressing Chinese hamster ovary cell line. Biotechnology Progress, 35(1), e2742.Journal article Mellahi, K., Brochu, D., Gilbert, M., Perrier, M., Ansorge, S., Durocher, Y., & Henry, O. (2019). Process intensification for the production of rituximab by an inducible CHO cell line. Bioprocess and Biosystems Engineering, 42(5), 711-725.
- 2018 (2)
Journal article Karengera, E., Robotham, A., Kelly, J., Durocher, Y., De Crescenzo, G., & Henry, O. (2018). Concomitant reduction of lactate and ammonia accumulation in fed-batch cultures: Impact on glycoprotein production and quality. Biotechnology Progress, 34(2), 494-504.Conference paper Durocher, Y., Toussaint, C., & Henry, O. (2018, May). Regulation of recombinant protein expression during CHO pool selection enhances high producer frequency [Abstract]. Cell Culture Engineering XVI, Tampa, FL, USA (1 page).
- 2017 (5)
Journal article Karengera, E., Robotham, A., Kelly, J., Durocher, Y., De Crescenzo, G., & Henry, O. (2017). Altering the central carbon metabolism of HEK293 cells: Impact on recombinant glycoprotein quality. Journal of Biotechnology, 242, 73-82.Journal article Riahi, N., Murschel, F., Lerouge, S., Durocher, Y., Henry, O., & De Crescenzo, G. (2017). Bioavailability of immobilized epidermal growth factor: Covalent versus noncovalent grafting. Biointerphases, 12(1), 010501 (8 pages).Journal article Karengera, E., Durocher, Y., De Crescenzo, G., & Henry, O. (2017). Combining metabolic and process engineering strategies to improve recombinant glycoprotein production and quality. Applied Microbiology and Biotechnology, 101(21), 7837-7851.Journal article Riahi, N., Liberelle, B., Henry, O., & De Crescenzo, G. (2017). Impact of RGD amount in dextran-based hydrogels for cell delivery. Carbohydrate Polymers, 161, 219-227.Journal article Venereo-Sánchez, A., Simoneau, M., Lanthier, S., Chahal, P., Bourget, L., Ansorge, S., Gilbert, R., Henry, O., & Kamen, A. (2017). Process intensification for high yield production of influenza H1N1 Gag virus-like particles using an inducible HEK-293 stable cell line. Vaccine, 35(33), 4220-4228.
- 2016 (4)
Journal article Venereo-Sánchez, A., Gilbert, R., Simoneau, M., Caron, A., Chahal, P., Chen, W., Ansorge, S., Li, X., Henry, O., & Kamen, A. (2016). Hemagglutinin and neuraminidase containing virus-like particles produced in HEK-293 suspension culture: An effective influenza vaccine candidate. Vaccine, 34(29), 3371-3380.Conference paper Karengera, E., De Crescenzo, G., Durocher, Y., & Henry, O. (2016, May). Improving the metabolic efficiency of mammalian cells and its impact on glycoproteins quality [Abstract]. Cell Culture Engineering XV, La Quinta (Palm Springs area), CA, USA (1 page).Journal article Toussaint, C., Henry, O., & Durocher, Y. (2016). Metabolic engineering of CHO cells to alter lactate metabolism during fed-batch cultures. Journal of Biotechnology, 217(C), 122-131.Journal article Riahi, N., Cappadocia, L., Henry, O., Omichinski, J., & De Crescenzo, G. (2016). Soluble expression, purification and functional characterization of a coil peptide composed of a positively charged and hydrophobic motif. Amino Acids, 48(2), 567-577.
- 2015 (1)
Journal article Thompson, C. M., Petiot, E., Mullick, A., Aucoin, M. G., Henry, O., & Kamen, A. A. (2015). Critical assessment of influenza VLP production in Sf9 and HEK293 expression systems. BMC Biotechnology, 15(1).
- 2014 (4)
Journal article Ghorbaniaghdam, A., Chen, J., Henry, O., & Jolicoeur, M. (2014). Analyzing Clonal Variation of Monoclonal Antibody-Producing CHO Cell Lines Using an In Silico Metabolomic Platform. PLOS One, 9(3).Journal article Ghorbaniaghdam, A., Henry, O., & Jolicoeur, M. (2014). An in-silico study of the regulation of CHO cells glycolysis. Journal of Theoretical Biology, 357, 112-122.Journal article Sheikholeslami, Z., Jolicoeur, M., & Henry, O. (2014). Elucidating the effects of postinduction glutamine feeding on the growth and productivity of CHO cells. Biotechnology Progress, 30(3), 535-546.Journal article Vallée, C., Durocher, Y., & Henry, O. (2014). Exploiting the metabolism of PYC expressing HEK293 cells in fed-batch cultures. Journal of Biotechnology, 169(1), 63-70.
- 2013 (5)
Journal article Ghorbaniaghdam, A., Henry, O., & Jolicoeur, M. (2013). A kinetic-metabolic model based on cell energetic state: study of CHO cells behaviour under Na-butyrate stimulation. Bioprocess and Biosystems Engineering, 36(4), 469-487.Journal article Thompson, C. M., Petiot, E., Lennaertz, A., Henry, O., & Kamen, A. A. (2013). Analytical technologies for influenza virus-like particle candidate vaccines: challenges and emerging approaches. Virology Journal, 10(1).Conference paper Thompson, C. M., Petiot, E., Aucoin, M. G., Henry, O., & Kamen, A. A. (2013, June). Developing a production process for influenza VLPs: a comparison between HEK 293SF and Sf9 production platforms [Poster]. 23rd European Society for Animal Cell Technology Meeting (ESACT 2013), Lille, France (2 pages). Published in BMC Proceedings, 7(S6).Journal article Sheikholeslami, Z., Jolicoeur, M., & Henry, O. (2013). Probing the metabolism of an inducible mammalian expression system using extracellular isotopomer analysis. Journal of Biotechnology, 164(4), 469-478.Journal article Sheikholeslami, Z., Jolicoeur, M., & Henry, O. (2013). The impact of the timing of induction on the metabolism and productivity of CHO cells in culture. Biochemical Engineering Journal, 79, 162-171.
- 2011 (3)
Journal article Henry, O., & Durocher, Y. (2011). Enhanced glycoprotein production in HEK-293 cells expressing pyruvate carboxylase. Metabolic Engineering, 13(5), 499-507.Journal article Ansorge, S., Lanthier, S., Transfiguracion, J., Henry, O., & Kamen, A. A. (2011). Monitoring lentiviral vector production kinetics using online permittivity measurements. Biochemical Engineering Journal, 54(1), 16-25.Journal article Henry, O., Jolicoeur, M., & Kamen, A. A. (2011). Unraveling the metabolism of HEK-293 cells using lactate isotopomer analysis. Bioprocess and Biosystems Engineering, 34(3), 263-73.
- 2010 (4)
Conference paper Ghorbaniaghdam, A., Henry, O., & Jolicoeur, M. (2010, July). A kinetic modelling approach to study the role of energy regulatory pathways in CHO cells [Paper]. 11th IFAC Symposium on Computer Applications in Biotechnology, Leuven, Belgium. Published in IFAC Proceedings Volumes, 43(6).Conference paper Henry, O., & Durocher, Y. (2010, July). Engineering of the Human Cell Line HEK-293 to Enhance Recombinant Protein Production [Paper]. 11th IFAC Symposium on Computer Applications in Biotechnology (CAB 2020), Leuven, Belgium. Published in IFAC Proceedings Volumes, 43(6).Journal article Ansorge, S., Henry, O., & Kamen, A. A. (2010). Recent progress in lentiviral vector mass production. Biochemical Engineering Journal, 48(3), 362-377.Journal article Le Ru, A., Jacob, D., Transfiguracion, J., Ansorge, S., Henry, O., & Kamen, A. A. (2010). Scalable Production of Influenza Virus in Hek-293 Cells for Efficient Vaccine Manufacturing. Vaccine, 28(21), 3661-3671.
- 2009 (1)
Journal article Ansorge, S., Lanthier, S., Transfiguracion, J., Durocher, Y., Henry, O., & Kamen, A. (2009). Development of a Scalable Process for High-Yield Lentiviral Vector Production by Transient Transfection of Hek293 Suspension Cultures. Journal of Gene Medicine, 11(10), 868-876.
- 2008 (1)
Journal article Henry, O., Kwok, E., & Piret, J. M. (2008). Simpler Noninstrumented Batch and Semicontinuous Cultures Provide Mammalian Cell Kinetic Data Comparable to Continuous and Perfusion Cultures. Biotechnology Progress, 24(4), 921-931.
- 2007 (2)
Conference paper Ansorge, S., Henry, O., Aucoin, M., Voyer, R., Carvell, J. P., & Kamen, A. (2007, June). Monitoring the Cell Size Distribution of Mammalian Cell Cultures Using On-Line Capacitance Measurements [Paper]. 20th ESACT Meeting, Dresden, Germany.Conference paper Henry, O., Ansorge, S., Aucoin, M., Voyer, R., & Kamen, A. (2007, June). On-line monitoring of cell size distribution in mammalian cell culture processes [Paper]. 10th IFAC Symposium on Computer Applications in Biotechnology, Cancun, Mexico. Published in IFAC Proceedings Volumes, 40(4).
- 2006 (2)
Conference paper Henry, O., Kamen, A., & Perrier, M. (2006, April). Monitoring the Physiological State of Mammalian Cell Perfusion Processes by on-Line Estimation of Intracellular Fluxes [Paper]. ADCHEM 2006 Symposium, Gramado, Brazil. Published in Journal of Process Control, 17(3).Conference paper Henry, O., Perrier, M., & Kamen, A. (2006, April). Monitoring the physiological state of mammalian cell perfusion processes by on-line estimation of intracellular fluxes [Paper]. International Symposium on Advanced Control of Chemical Processes, Gramado, Brazil.
- 2005 (1)
Journal article Henry, O., Perrier, M., & Kamen, A. (2005). Metabolic Flux Analysis of Hek-293 Cells in Perfusion Cultures for the Production of Adenoviral Vectors. Metabolic Engineering, 7(5-6), 467-476.
- 2004 (4)
Thesis Henry, O. (2004). Caractérisation et modélisation de la production de vecteurs adénoviraux dans un bioréacteur opérant en mode perfusion [Ph.D. thesis, École Polytechnique de Montréal].Journal article Kamen, A., & Henry, O. (2004). Development and optimization of an adenovirus production process. Journal of Gene Medicine, 6(S1), S184-S192.Journal article Henry, O., Dormond, E., Perrier, M., & Kamen, A. (2004). Insights into adenoviral vector production kinetics in acoustic filter-based perfusion cultures. Biotechnology and Bioengineering, 86(7), 765-774.Conference paper Henry, O., Perrier, M., & Kamen, A. (2004, March). On-line monitoring of adenovirus production in perfusion cultures [Paper]. 9th International Symposium on Computer Applications in Biotechnology (CAB9), Nancy, France.
- 2003 (2)
Conference paper Henry, O., Perrier, M., & Kamen, A. (2003, September). Optimization of adenovirus production in perfusion cultures using an ultrasonic retention device [Paper]. 6th Conference on Protein Expression in Animal Cells, Mont-Tremblant.Conference paper Kamen, A., Henry, O., Jacob, D., & Bernier, A. (2003, May). Successful development of a robust adenovirus production process primarily relies on a better understanding of packaging cell line physiology and vector replication kinetics [Paper]. 18th ESACT Meeting, Granada, Spain.
- 2001 (1)
Conference paper Nadeau, I., Henry, O., Jacob, D., Perrier, M., & Kamen, A. (2001, June). Effect of Medium Composition on the 293SF Central Metabolic Fluxes during Growth and Infection with Adenovirus [Paper]. 8th International Symposium on Computer Applications in Biotechnology (CAB8), Québec City, Qc.
