Blanquez-Yeste, V., Janelle, F., Tran, T., Ember, K., Sheehy, G., Dallaire, F., Marple, E., Urmey, K., Labidi, M., & Leblond, F. (2025). Development and preclinical evaluation of an endonasal Raman spectroscopy probe for transsphenoidal pituitary adenoma surgery. Journal of Biomedical Optics, 30(03), 035004 (17 pages).
Directory of Experts
Leblond, Frédéric

Directory of Experts
Leblond, Frédéric
Directory of Experts
Publications by date
Journal article (86)
Conference paper (45)
Book
Book chapter (1)
Patent (3)
Report
Thesis
Dataset
Teaching resource
Image
Audio recording
Video recording
Other
Frédéric Leblond (135)
- 2025 (6)
Journal article Conference paper Blanquez-Yeste, V., Janelle, F., Tran, T., Sheehy, G., Dallaire, F., Labidi, M., Cayrol, R., & Leblond, F. (2025, January). Development of an endonasal Raman spectroscopy probe for pituitary adenoma surgery [Paper]. Photonics West 2025, San Francisco, CA, USA (11 pages).Journal article Dulude, J.-P., Le Moël, A., Dallaire, F., Doyon, J., Urmey, K., Marple, E., Leblanc, G., Basile, G., Mottard, S., Isler, M., Leblond, F., & Gervais, M.-K. (2025). Intraoperative use of high-speed Raman spectroscopy during soft tissue sarcoma resection. Scientific Reports, 15(1), 13 pages.Journal article Daoust, F., Dallaire, F., Tavera, H., Ember, K., Guiot, M.-C., Petrecca, K., & Leblond, F. (2025). Preliminary study demonstrating cancer cells detection at the margins of whole glioblastoma specimens with Raman spectroscopy imaging. Scientific Reports, 15(1), 15 pages.Journal article Leblond, F., Dallaire, F., Ember, K., Le Moël, A., Blanquez-Yeste, V., Tavera, H., Sheehy, G., Trang, T., Guiot, M.-C., Weil, A. G., Dudley, R., Hadjipanayis, C. G., & Petrecca, K. (2025). Quantitative assessment of the generalizability of a brain tumor Raman spectroscopy machine learning model to various tumor types including astrocytoma and oligodendroglioma. Journal of Biomedical Optics, 30(01), 010501 (7 pages).Journal article Tran, T., Dallaire, F., Sonnen, J. A., Cayrol, R., Leblond, F., & Dudley, R. (2025). Single-cell Raman spectroscopy detects pediatric focal cortical dysplasia. Biophotonics discovery., 2(01), 015002 (12 pages).
- 2024 (9)
Conference paper Lee, S. S., Beaudoin, G., Yeoh, J. H., Leblond, F., Trifiro, M., & Paliouras, M. (2024, April). Abstract 4168: Pre-clinical demonstration of Raman spectroscopy-assisted photothermal therapy for prostate cancer [Paper]. AACR Annual Meeting 2024, San Diego, California. Published in Cancer Research, 84(6_Suppl.).Journal article Ember, K., Dallaire, F., Plante, A., Sheehy, G., Guiot, M.-C., Agarwal, R., Yadav, R., Douet, A., Selb, J., Tremblay, J. P., Dupuis, A., Marple, E., Urmey, K., Rizea, C., Harb, A., McCarthy, L., Schupper, A., Umphlett, M., Tsankova, N., ... Petrecca, K. (2024). In situ brain tumor detection using a Raman spectroscopy system — results of a multicenter study. Scientific Reports, 14, 14 (12 pages).Journal article Ember, K. J. I., Ksantini, N., Dallaire, F., Sheehy, G., Tran, T., Dehaes, M., Durand, M., Trudel, D., & Leblond, F. (2024). Liquid saliva-based Raman spectroscopy device with on-board machine learning detects COVID-19 infection in real-time. The Analyst, 149(22), 5535-5545.Journal article David, S., Tavera, H., Tran, T., Dallaire, F., Daoust, F., Tremblay, F., Richer, L., Meterissian, S., & Leblond, F. (2024). Macroscopic inelastic scattering imaging using a hyperspectral line-scanning system identifies invasive breast cancer in lumpectomy and mastectomy specimens. Journal of Biomedical Optics, 29(6), 065004 (16 pages).Conference paper Ember, K., Ksantini, N., Dallaire, F., Sheehy, G., Noé, A., Tran, T., Durand, M., Trudel, D., & Leblond, F. (2024, January). Rapid detection of COVID-19 in liquid saliva using reagent-free Raman spectroscopy [Presentation]. In SPIE Photonics West 2024, San Francisco, California, United States.Journal article Grajales, D., Le, W. T., Tran, T., David, S., Dallaire, F., Ember, K., Leblond, F., Menard, C., & Kadoury, S. (2024). Robot-assisted biopsy sampling for online Raman spectroscopy cancer confirmation in the operating room. International Journal of Computer Assisted Radiology and Surgery, 9-9.Journal article Zamani, E., Ksantini, N., Sheehy, G., Ember, K. J. I., Baloukas, B., Zabeida, O., Tran, T., Mahfoud, M., Sapieha, J.-E., Martinu, L., & Leblond, F. (2024). Spectral effects and enhancement quantification in healthy human saliva with surface-enhanced Raman spectroscopy using silver nanopillar substrates. Lasers in Surgery and Medicine, 56(2), 206-217.Journal article David, S., Ksantini, N., Dallaire, F., Ember, K., Daoust, F., Sheehy, G., Hadjipanayis, C. G., Petrecca, K., Wilson, B. C., & Leblond, F. (2024). Toward noncontact macroscopic imaging of multiple cancers using multi-spectral inelastic scattering detection. Journal of Biophotonics, 2024000087 (7 pages).Conference paper Leblond, F., David, S., Pahlavani, S., Ksantini, N., Dallaire, F., Sheehy, G., Hadjapanayis, C., Petrecca, K., & Wilson, B. C. (2024, January). Towards non-contact and real-time large field-of-view single-band Raman spectroscopy imaging in brain cancer surgery [Presentation]. In SPIE Photonics West 2024, San Francisco, Ca, United States.
- 2023 (13)
Journal article Daoust, F., Tavera, H., Dallaire, F., Orsini, P., Savard, K., Bismuth, J., McKoy, P., Veilleux, I., Petrecca, K., & Leblond, F. (2023). A clinical Raman spectroscopy imaging system and safety requirements for in situ intraoperative tissue characterization. Analyst, 148(9), 1991-2001.Book chapter Ember, K., Dulude, J.-P., Tran, T., Gervais, M.-K., Meterissian, S., Dudley, R., Petrecca, K., & Leblond, F. (2023). Clinical Aspects of Raman Spectroscopy in Surgical Applications. In Sato, H., Popp, J., Wood, B. R., & Ozaki, Y. (eds.), Raman Spectroscopy in Human Health and Biomedicine (pp. 553-585).Conference paper Sheehy, G., & Leblond, F. (2023, October). Creating Open-Source software packages for Raman spectrum processing and analysis [Abstract]. Advances in Optics for Biotechnology, Medicine and Surgery (OPTICS 2023), Tomar, Portugal (1 page).Journal article Bido, A. T., Ember, K. J. I., Trudel, D., Durand, M., Leblond, F., & Brolo, A. G. (2023). Detection of SARS-CoV-2 in saliva by a low-cost LSPR-based sensor. Analytical Methods, 32(32), 3955-3966.Journal article David, S., Tran, T., Dallaire, F., Sheehy, G., Azzi, F., Trudel, D., Tremblay, F., Ömeroğlu, A., Leblond, F., & Meterissian, S. (2023). In situ Raman spectroscopy and machine learning unveil biomolecular alterations in invasive breast cancer. Journal of Biomedical Optics, 28(3), 036009 (18 pages).Patent Valdes, P., Leblond, F., Paulsen, K. D., Campbell Wilson, B., Roberts, D. W., & Jermyn, M. (2023). Method and apparatus for quantitative and depth resolved hyperspectral fluorescence and reflectance imaging for surgical guidance. (Patent Application no. US20230075997).Journal article Sheehy, G., Picot, F., Dallaire, F., Ember, K., Nguyen, T., Petrecca, K., Trudel, D., & Leblond, F. (2023). Open-sourced Raman spectroscopy data processing package implementing a baseline removal algorithm validated from multiple datasets acquired in human tissue and biofluids. Journal of Biomedical Optics, 28(2), 025002 (20 pages).Journal article Košík, I., Dallaire, F., Pires, L., Tran, T., Leblond, F., & Wilson, B. (2023). Preclinical evaluation of Raman spectroscopy for pedicular screw insertion surgical guidance in a porcine spine model. Journal of Biomedical Optics, 28(5), 057003 (15 pages).Conference paper Orsini, P., Desroches, J., Daoust, F., Tavera, H., Dallaire, F., Savard, K., Bismuth, J., McKoy, P., Veilleux, I., Petrecca, K., & Leblond, F. (2023, January). Raman macroscopic imaging system for intraoperative brain cancer detection [Paper]. SPIE BiOS 2023, San Francisco, California.Journal article Gagnon, J. R., Allen, C. H., Trudel, D., Leblond, F., Stys, P. K., Brideau, C., & Murugkar, S. (2023). Spectral focusing-based stimulated Raman scattering microscopy using compact glass blocks for adjustable dispersion. Biomedical Optics Express, 14(6), 2510-2522.Journal article Leblond, F., Dallaire, F., Trang, T., Yadav, R., Aubertin, K., Goudie, E., Roméo, P., Kent, C., Leduc, C., & Liberman, M. (2023). Subsecond lung cancer detection within a heterogeneous background of normal and benign tissue using single-point Raman spectroscopy. Journal of Biomedical Optics, 28(9), 090501 (8 pages).Conference paper Grajales, D., Le, W., Dallaire, F., Sheehy, G., David, S., Tran, T., Leblond, F., Ménard, C., & Kadoury, S. (2023, October). Towards Real-Time Confirmation of Breast Cancer in the OR Using CNN-Based Raman Spectroscopy Classification [Paper]. 2nd International Workshop on Cancer Prevention Through Early Detection (CaPTion 2023), Vancouver, BC, Canada.Conference paper Leblond, F. (2023, October). What role in surgery for Raman spectroscopy ? [Abstract]. Advances in Optics for Biotechnology, Medicine and Surgery (OPTICS 2023), Tomar, Portugal (1 page).
- 2022 (9)
Conference paper Maubois, B., Ksantini, N., & Leblond, F. (2022, April). Development of a time-domain tissue imaging Raman spectroscopy system increasing inelastic scattering signal-to-background ratio from early-photon time gating [Paper]. Clinical and Translational Biophotonics 2022, Fort Lauderdale, FL, USA.Journal article Lopera, D. O. G., Picot, F., Shams, R., Dallaire, F., Sheehy, G., Alley, S., Barkati, M., Delouya, G., Carrier, J.-F., Birlea, M., Trudel, D., Leblond, F., Ménard, C., & Kadoury, S. (2022). Image-guided Raman spectroscopy navigation system to improve transperineal prostate cancer detection. Part 2: in-vivo tumor-targeting using a classification model combining spectral and MRI-radiomics features. Journal of Biomedical Optics, 27(9), 095004 (16 pages).Journal article Picot, F., Shams, R., Dallaire, F., Sheehy, G., Tran, T., Grajales, D., Birlea, M., Trudel, D., Ménard, C., Kadoury, S., & Leblond, F. (2022). Image-guided Raman spectroscopy navigation system to improve transperineal prostate cancer detection. Part 1: Raman spectroscopy fiber-optics system and in situ tissue characterization. Journal of Biomedical Optics, 27(9), 095003 (14 pages).Journal article Blais-Ouellette, S., Rooney, D., Heller, D. A., Roxbury, D., Leblond, F., & Akbarzadeh, A. (2022). (Invited) Advances in Swir In Vivo Fluorescence Imaging Instrumentation. Meeting abstracts, MA2022-01(8), 676-676.Journal article Laurence, A., Toffa, D. H., Peng, K., Robert, M., Bouthillier, A., Nguyen, D. K., & Leblond, F. (2022). Multispectral intraoperative imaging for the detection of the hemodynamic response to interictal epileptiform discharges. Biomedical Optics Express, 13(12), 6245-6257.Journal article David, S., Plante, A., Dallaire, F., Tremblay, J.-P., Sheehy, G., Macdonald, E., Forrest, L., Daneshmand, M., Trudel, D., Wilson, B. C., Hopkins, L., Murugkar, S., Vanderhyden, B., & Leblond, F. (2022). Multispectral label-free Raman spectroscopy can detect ovarian and endometrial cancer with high accuracy. Journal of Biophotonics, 15(2), 10 pages.Journal article Ciobanu, C., Ember, K. J. I., Nyíri, B. J., Rajan, S., Chauhan, V., Leblond, F., & Murugkar, S. (2022). Potential of Raman Spectroscopy for Blood-Based Biopsy. IEEE Instrumentation & Measurement Magazine, 25(1), 62-68.Journal article Ember, K., Daoust, F., Mahfoud, M., Dallaire, F., Ahmad, E. Z., Tran, T., Plante, A., Diop, M.-K., Nguyen, T., St-Georges-Robillard, A., Ksantini, N., Lanthier, J., Filiatrault, A., Sheehy, G., Beaudoin, G., Quach, C., Trudel, D., & Leblond, F. (2022). Saliva-based detection of COVID-19 infection in a real-world setting using reagent-free Raman spectroscopy and machine learning. Journal of Biomedical Optics, 27(2), 025002 (24 pages).Journal article Ksantini, N., Veilleux, I., De Denus-Baillargeon, M.-M., Orsini, P., Dicaire, I., Lecourt, J.-B., Gognau, A., Hernandez, Y., Baylon, A., Massabki, M., Lesage, F., & Leblond, F. (2022). Time-gated interferometric detection increases Raman scattering to fluorescence signal ratio in biological samples. Journal of Biophotonics, 15(1), 6 pages.
- 2021 (4)
Journal article Plante, A., Dallaire, F., Grosset, A.-A., Nguyen, T., Birlea, M., Wong, J., Daoust, F., Roy, N., Kougioumoutzakis, A., Azzi, F., Aubertin, K., Kadoury, S., Latour, M., Albadine, R., Prendeville, S., Boutros, P., Fraser, M., Bristow, R. G., Van Der Kwast, T., ... Leblond, F. (2021). Dimensional reduction based on peak fitting of Raman micro spectroscopy data improves detection of prostate cancer in tissue specimens. Journal of Biomedical Optics, 26(11), 14 pages.Journal article Daoust, F., Nguyen, T., Orsini, P., Bismuth, J., De Denus-Baillargeon, M.-M., Veilleux, I., Wetter, A., McKoy, P., Dicaire, I., Massabki, M., Petrecca, K., & Leblond, F. (2021). Handheld macroscopic Raman spectroscopy imaging instrument for machine-learning-based molecular tissue margins characterization. Journal of Biomedical Optics, 26(2), 18 pages.Conference paper Grajales, D., Picot, F., Shams, R., Barkati, M., Delouya, G., Béliveau-Nadeau, D., Nicolas, B., Leblond, F., Ménard, C., & Kadoury, S. (2021, October). In Vivo Confirmation of Prostate Tumor Burden During HDR Brachytherapy With a Combined Raman Spectroscopy and MRI Radiomics Approach [Abstract]. ASTRO 63rd Annual Meeting, Chicago, Illinois. Published in International Journal of Radiation Oncology Biology Physics, 111(3 (suppl.)).Journal article Shabestri, B., Anastasio, M. A., Fei, B., & Leblond, F. (2021). Special Series Guest Editorial: Artificial Intelligence and Machine Learning in Biomedical Optics. Journal of Biomedical Optics, 26(5), 4 pages.
- 2020 (12)
Conference paper Picot, F., Sheehy, G., Dallaire, F., Tremblay, J.-P., Daoust, F., Lemoine, É., Chaikho, L., Bégin, T., Petrecca, K., Kadoury, S., Leblond, F., Elson, D. S., Gioux, S., & Pogue, B. W. (2020, April). Data compatibility across point probe Raman spectroscopy systems and its impact on statistical models portability (Conference Presentation) [Presentation]. In Clinical Biophotonics 2020.Journal article Picot, F., Daoust, F., Sheehy, G., Dallaire, F., Chaikho, L., Bégin, T., Kadoury, S., & Leblond, F. (2020). Data consistency and classification model transferability across biomedical Raman spectroscopy systems. Translational Biophotonics, 3(1), 1-11.Journal article Akbarzadeh, A., Edjlali, E., Sheehy, G., Selb, J., Agarwal, R., Weber, J., & Leblond, F. (2020). Experimental validation of a spectroscopic Monte Carlo light transport simulation technique and Raman scattering depth sensing analysis in biological tissue. Journal of Biomedical Optics, 25(10), 105002 (19 pages).Journal article Grosset, A.-A., Dallaire, F., Nguyen, T., Birlea, M., Wong, J., Daoust, F., Roy, N., Kougioumoutzakis, A., Azzi, F., Aubertin, K., Kadoury, S., Latour, M., Albadine, R., Prendeville, S., Boutros, P., Fraser, M., Bristow, R. G., van der Kwast, T., Orain, M., ... Trudel, D. (2020). Identification of intraductal carcinoma of the prostate on tissue specimens using Raman micro-spectroscopy: A diagnostic accuracy case-control study with multicohort validation. Plos Medicine, 17(8), e1003281 (20 pages).Conference paper Leblond, F., Wax, A., & Backman, V. (2020, February). In situ molecular characterization and brain cancer detection using macroscopic spontaneous Raman spectroscopy imaging (Conference Presentation) [Presentation]. In Biomedical Applications of Light Scattering X, San Francisco, California, United States.Conference paper Daoust, F., Orsini, P., Bismuth, J., De Denus-Baillargeon, M.-M., Veilleux, I., Wetter, A., McKoy, P., Dicaire, I., Massabki, M., Petrecca, K., Leblond, F., Petrich, W., & Huang, Z. (2020, February). Large field of view macroscopic Raman line-scanning imaging system for neuro-oncology applications (Conference Presentation) [Presentation]. In Biomedical Vibrational Spectroscopy 2020: Advances in Research and Industry, San Francisco, California, United States.Conference paper Laurence, A., Peng, K., Toffa, D., Robert, M., Lesage, F., Bouthillier, A., Nguyen, D. K., & Leblond, F. (2020, April). Localization of epileptic activity based on hemodynamics using an intraoperative hyperspectral imaging system [Paper]. Clinical and Translational Biophotonics, Washington, D.C..Journal article Laurence, A., Bouthillier, A., Robert, M., Nguyen, D. K., & Leblond, F. (2020). Multispectral diffuse reflectance can discriminate blood vessels and bleeding during neurosurgery based on low-frequency hemodynamics. Journal of Biomedical Optics, 25(11), 10 pages.Journal article Shams, R., Picot, F., Grajales, D., Sheehy, G., Dallaire, F., Birlea, M., Saad, F., Trudel, D., Ménard, C., Leblond, F., & Kadoury, S. (2020). Pre-clinical evaluation of an image-guided in-situ Raman spectroscopy navigation system for targeted prostate cancer interventions. International Journal of Computer Assisted Radiology and Surgery, 15(5), 867-876.Journal article Dallaire, F., Picot, F., Tremblay, J.-P., Sheehy, G., Lemoine, É., Agarwal, R., Kadoury, S., Trudel, D., Lesage, F., Petrecca, K., & Leblond, F. (2020). Quantitative spectral quality assessment technique validated using intraoperative in vivo Raman spectroscopy measurements. Journal of Biomedical Optics, 25(4).Journal article Depaoli, D., Lemoine, É., Ember, K., Parent, M., Prud'Homme, M., Cantin, L., Petrecca, K., Leblond, F., & Cote, D. C. (2020). Rise of Raman spectroscopy in neurosurgery: A review. Journal of Biomedical Optics, 25(5), 36 pages.Journal article Beaulieu, É., Laurence, A., Birlea, M., Sheehy, G., Angulo-Rodriguez, L., Latour, M., Albadine, R., Saad, F., Trudel, D., & Leblond, F. (2020). Wide-field optical spectroscopy system integrating reflectance and spatial frequency domain imaging to measure attenuation-corrected intrinsic tissue fluorescence in radical prostatectomy specimens. Biomedical Optics Express, 11(4), 2052-2072.
- 2019 (8)
Journal article Desroches, J., Lemoine, É., Pinto, M., Marple, E., Urmey, K., Diaz, R., Guiot, M.-C., Wilson, B. C., Petrecca, K., & Leblond, F. (2019). Development and first in-human use of a Raman spectroscopy guidance system integrated with a brain biopsy needle. Journal of Biophotonics, 12(3), e201800396 (7 pages).Journal article Lemoine, É., Dallaire, F., Yadav, R., Agarwal, R., Kadoury, S., Trudel, D., Guiot, M.-C., Petrecca, K., & Leblond, F. (2019). Feature engineering applied to intraoperative in vivo Raman spectroscopy sheds light on molecular processes in brain cancer: a retrospective study of 65 patients. Analyst, 144(22), 6517-6532.Journal article Pinto, M., Zorn, K. C., Tremblay, J.-P., Desroches, J., Dallaire, F., Aubertin, K., Marple, E., Kent, C., Leblond, F., Trudel, D., & Lesage, F. (2019). Integration of a Raman spectroscopy system to a robotic-assisted surgical system for real-time tissue characterization during radical prostatectomy procedures. Journal of Biomedical Optics, 24(2), 025001 (10 pages).Journal article Picot, F., Goyette, A., Obaid, S., Desroches, J., Lessard, S., Tremblay, M.-A., Strupler, M., Wilson, B., Petrecca, K., Soulez, G., & Leblond, F. (2019). Interstitial imaging with multiple diffusive reflectance spectroscopy projections for in vivo blood vessels detection during brain needle biopsy procedures. Neurophotonics, 6(2), 025003 (8 pages).Journal article St-Georges-Robillard, A., Cahuzac, M., Péant, B., Fleury, H., Lateef, M. A., Ricard, A., Sauriol, A., Leblond, F., Mes-Masson, A.-M., & Gervais, T. (2019). Long-term fluorescence hyperspectral imaging of on-chip treated co-culture tumour spheroids to follow clonal evolution. Integrative Biology, 11(4), 130-141.Conference paper Laurence, A., Beaulieu, É., Nguyen, D. K., Bouthillier, A., Trudel, D., & Leblond, F. (2019, June). Multimodal imaging platform for surgical guidance during epilepsy surgery [Paper]. Diffuse Optical Spectroscopy and Imaging VII, Munich, Germany (4 pages).Journal article Sibai, M., Wirth, D. J., Leblond, F., Roberts, D. W., Paulsen, K. D., & Wilson, B. C. (2019). Quantitative subsurface spatial frequency-domain fluorescence imaging for enhanced glioma resection. Journal of Biophotonics, 12(5), 6 pages.Conference paper Shaikh, R., Guiot, M.-C., Petrecca, K., Tchaya, M., & Leblond, F. (2019, April). Raman micro-spectroscopic study on brain tissue mapping [Paper]. Bio-Optics: Design and Application (BODA 2019), Tucson, AZ.
- 2018 (11)
Journal article Desroches, J., Jermyn, M., Pinto, M., Picot, F., Tremblay, M.-A., Obaid, S., Marple, E., Urmey, K., Trudel, D., Soulez, G., Guiot, M.-C., Wilson, B. C., Petrecca, K., & Leblond, F. (2018). A new method using Raman spectroscopy for in vivo targeted brain cancer tissue biopsy. Scientific Reports, 8(1).Journal article Wilson, B. C., Jermyn, M., & Leblond, F. (2018). Challenges and opportunities in clinical translation of biomedical optical spectroscopy and imaging. Journal of Biomedical Optics, 23(3), 13 pages.Journal article Aubertin, K., Desroches, J., Jermyn, M., Trinh, V. Q., Saad, F., Trudel, D., & Leblond, F. (2018). Combining high wavenumber and fingerprint raman spectroscopy for the detection of prostate cancer during radical prostatectomy. Biomedical Optics Express, 9(9), 4294-4305.Journal article St-Arnaud, K., Aubertin, K., Strupler, M., Madore, W.-J., Grosset, A.-A., Petrecca, K., Trudel, D., & Leblond, F. (2018). Development and characterization of a handheld hyperspectral Raman imaging probe system for molecular characterization of tissue on mesoscopic scales. Medical Physics, 45(1), 328-339.Conference paper Picot, F., Goyette, A., Pichette, J., Tremblay, M.-A., Desroches, J., Obaïd, S., Lessard, S., Soulez, G., & Leblond, F. (2018, April). Diffusive reflectance spectroscopy to enhance safety during brain biopsy procedure [Paper]. Biophotonics Congress (Optical Tomography and Spectroscopy 2018), Hollywood, Florida.Journal article St-Georges-Robillard, A., Masse, M., Cahuzac, M., Strupler, M., Patra, B., Orimoto, A. M., Kendall-Dupont, J., Péant, B., Mes-Masson, A.-M., Leblond, F., & Gervais, T. (2018). Fluorescence hyperspectral imaging for live monitoring of multiple spheroids in microfluidic chips. Analyst, 143(16), 3829-3840.Conference paper Desroches, J., Jermyn, M., Marple, E., Urmey, K., Soulez, G., Guiot, M.-C., Wilson, B. C., Petrecca, K., Leblond, F., Vo-Dinh, T., Mahadevan-Jansen, A., & Grundfest, W. S. (2018, January). Integrated Raman biopsy probe for high yield targeted brain cancer biopsies (Conference Presentation) [Presentation]. In SPIE BiOS, San Francisco, California, United States.Conference paper Leblond, F., Biggs, G., Pogue, B. W., & Gioux, S. (2018, January). Label-free optical spectroscopy techniques for targeted, real time and informed in situ cancer diagnosis (Conference Presentation) [Presentation]. In Molecular-Guided Surgery: Molecules, Devices, and Applications IV, San Francisco, California, United States.Journal article Aubertin, K., Quoc-Trinh, V., Jermyn, M., Baksic, P., Grosset, A.-A., Desroches, J., St-Arnaud, K., Birlea, M., Vladoiu, M. C., Latour, M., Albadine, R., Saad, F., Leblond, F., & Trudel, D. (2018). Mesoscopic characterization of prostate cancer using Raman spectroscopy : potential for diagnostics and therapeutics. BJU International, 122(2), 326-336.Conference paper St-Georges-Robillard, A., Cahuzac, M., Sauriol, A., Peant, B., Mes-Masson, A.-M., Leblond, F., & Gervais, T. (2018, November). Quantifying ParPi-resistant subpopulations after treatment in co-culture spheroids using hyperspectral imaging [Paper]. 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2018), Kaohsiung, Taiwan.Journal article Roberts, D. W., Olson, J. D., Evans, L. T., Kolste, K. K., Kanick, S. C., Fan, X., Bravo, J. J., Wilson, B. C., Leblond, F., Marois, M., & Paulsen, K. D. (2018). Red-light excitation of protoporphyrin IX fluorescence for subsurface tumor detection. Journal of Neurosurgery, 128(6), 1690-1697.
- 2017 (16)
Conference paper St-Georges-Robillard, A., Masse, M., Patra, B., Orimoto, A. M., Strupler, M., Mes-Masson, A.-M., Leblond, F., & Gervais, T. (2017, October). Chemosensitivity analysis of co-culture spheroids on-chip using hyperspectral fluorescence imaging [Paper]. 21st International Conference on Miniaturization in Chemistry and the Life Sciences (microTAS), Savannah, GA, ÉU.Conference paper St-Georges-Robillard, A., Masse, M., Patra, B., Orimoto, A. M., Strupler, M., Mes-Masson, A.-M., Leblond, F., & Gervais, T. (2017, October). Chemosensitivity analysis of co-culture tumor spheroids on chip using hyperspectral fluorescence imaging [Paper]. 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017), Savannah, GA, USA.Journal article St-Pierre, C., Madore, W.-J., De Montigny, É., Trudel, D., Boudoux, C., Godbout, N., Mes-Masson, A.-M., Rahimi, K., & Leblond, F. (2017). Dimension reduction technique using a multilayered descriptor for high-precision classification of ovarian cancer tissue using optical coherence tomography: a feasibility study. Journal of Medical Imaging, 4(4), 13 pages.Journal article Wirth, D., Kolste, K., Kanick, S., Roberts, D. W., Leblond, F., & Paulsen, K. D. (2017). Fluorescence depth estimation from wide-field optical imaging data for guiding brain tumor resection: A multi-inclusion phantom study. Biomedical Optics Express, 8(8), 3656-3670.Journal article Jermyn, M., Mercier, J., Aubertin, K., Desroches, J., Urmey, K., Karamchandiani, J., Marple, E., Guiot, M.-C., Leblond, F., & Petrecca, K. (2017). Highly Accurate Detection of Cancer In Situ with Intraoperative, Label-Free, Multimodal Optical Spectroscopy. Cancer Research, 77(14), 3942-3950.Conference paper Desroches, J., Jermyn, M., Pinto, M., Picot, F., Tremblay, M.-A., Obaïd, S., Guiot, M.-C., Petrecca, K., Wilson, B. C., & Leblond, F. (2017, April). High wavenumber Raman spectroscopy to improve diagnostic yield of brain needle biopsies [Paper]. Optics and the Brain 2017, San Diego, California, United States.Conference paper Grosset, A.-A., St-Pierre, C., Jermyn, M., Aubertin, K., Kougioumoutzakis, A., Pineau, M., St-Arnaud, K., Vladoiu, M. C., Leblond, F., & Trudel, D. (2017, March). Improving Diagnostic Accuracy in the Pathology Workflow by Integration of Raman Microscopy [Abstract]. 106th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP 2017), San Antonio, TX. Published in Modern Pathology, 30(S2).Journal article Gough, K. M., & Leblond, F. (2017). Optical diagnosis: Highlighting the clinical applications of vibrational spectroscopy. Analyst, 142(8), 1177-1178.Journal article Sibai, M., Fisher, C., Veilleux, I., Elliott, J. T., Leblond, F., Roberts, D. W., & Wilson, B. C. (2017). Preclinical evaluation of spatial frequency domain-enabled wide-field quantitative imaging for enhanced glioma resection. Journal of Biomedical Optics, 22(7), 10 pages.Conference paper Grosset, A.-A., St-Pierre, C., St-Arnaud, K., Aubertin, K., Jermyn, M., Leblond, F., & Trudel, D. (2017, December). Raman microscopy to assess biochemical recurrence risk after radical prostatectomy [Poster]. AACR Special Conference on Prostate Cancer: Advances in Basic, Translational, and Clinical Research, Orlando, Florida, USA. Published in Cancer Research, 78(16).Conference paper Aubertin, K., Quoc-Huy, T., Jermyn, M., St-Pierre, C., Vladoiu, M.-C., Grosset, A.-A., Saad, F., Trudel, D., & Leblond, F. (2017, January). Raman spectroscopy for prostate cancer detection and characterization (Conference Presentation) [Paper]. Therapeutics and Diagnostics in Urology: Lasers, Robotics, Minimally Invasive and Advanced Biomedical Devices, USA.Journal article Desroches, J., Laurence, A., Jermyn, M., Pinto, M., Tremblay, M.-A., Petrecca, K., & Leblond, F. (2017). Raman spectroscopy in microsurgery: impact of operating microscope illumination sources on data quality and tissue classification. Analyst, 142(8), 1185-1191.Patent Leblond, F., Petrecca, K., & Jermyn, M. (2017). System and method for assessing a cancer status of biological tissue. (Patent Application no. US20170020460).Conference paper Leblond, F. (2017, January). Taking label-free optical spectroscopy techniques into the operating theatre: biopsy needles and surgical guidance probes [Paper]. Optical Biopsy XV: Toward Real-Time Spectroscopic Imaging and Diagnosis, USA (1 page).Conference paper Pinto, M., Aubertin, K., Desroches, J., Jermyn, M., Trinh, V. Q.-H., Vladoiu, M. C., Grosset, A. A., Lavallee, A. P., Benzyane, I., Benzyane, I., Benzyane, I., Faci, N., Richard, M. E., Duong, L., Haas, C., Badawy, Y., Saad, F., Zorn, K., Lesage, F., ... Trudel, D. (2017, April). Towards live detection of cancerous tissue during radical prostatectomy using a raman spectroscopy probe [Paper]. Bio-Optics: Design and Application (BODA 2017), San Diego, CA, United States.Conference paper Aubertin, K., Birlea, M., Pinto, M., St-Arnaud, K., Trinh, V. Q., Grosset, A.-A., Leblond, F., & Trudel, D. (2017, December). Towards the use of Raman spectroscopy to guide prostate biopsy procedure [Poster]. AACR Special Conference on Prostate Cancer: Advances in Basic, Translational, and Clinical Research, Orlando, Florida. Published in Cancer Research, 78(16).
- 2016 (13)
Conference paper Madsen, S. J., Yang, V. X. D., Jansen, E. D., Luo, Q., Mohanty, S. K., Thakor, N. V., Angulo-Rodríguez, L. M., Laurence, A., Jermyn, M., Sheehy, G., Sibai, M., Petrecca, K., Roberts, D. W., Paulsen, K. D., Wilson, B. C., & Leblond, F. (2016, February). An intraoperative spectroscopic imaging system for quantification of protoporphyrin IX during glioma surgery [Paper]. Clinical and Translational Neurophotonics, part of Photonics West 2016, San Francisco, California, United States.Journal article Jermyn, M., Desroches, J., Aubertin, K., St-Arnaud, K., Madore, W.-J., De Montigny, E., Guiot, M.-C., Trudel, D., Wilson, B. C., Petrecca, K., & Leblond, F. (2016). A review of Raman spectroscopy advances with an emphasis on clinical translation challenges in oncology. Physics in Medicine and Biology, 61(23), R370-R400.Patent Leblond, F., Wilson, B., Goyette, A., Pichette, J., Petrecca, K., Boudoux, C., Madore, W.-J., & Strupler, M. (2016). Biopsy device and method for obtaining a tomogram of a tissue volume using same. (Patent Application no. US20160151055).Conference paper Picot, F., Pichette, J., Desroches, J., Goyette, A., Tremblay, M.-A., Ben-Mansour, Y., Leblond, F., Soulez, G., & Wilson, B. C. (2016, May). Imaging system based on diffusive reflectance spectroscopy for blood vessels detection during brain biopsy procedure [Paper]. Photonics North 2016, Québec City, Québec (1 page).Conference paper Laurence, A., Pichette, J., Angulo-Rodríguez, L. M., Saint Pierre, C., Lesage, F., Bouthillier, A., Nguyen, D. K., & Leblond, F. (2016, February). Intraoperative brain hemodynamic response assessment with real-time hyperspectral optical imaging [Paper]. Clinical and Translational Neurophotonics, part of Photonics West 2016, San Francisco, California, United States.Journal article Pichette, J., Laurence, A., Angulo, L., Lesage, F., Bouthillier, A., Nguyen, D. K., & Leblond, F. (2016). Intraoperative video-rate hemodynamic response assessment in human cortex using snapshot hyperspectral optical imaging. Neurophotonics, 3(4).Journal article Astolfi, M., St-Georges-Robillard, A., Leblond, F., Mes-Masson, A.-M., & Gervais, T. (2016). Microfluidics and spectroscopic imaging for personalized medicine in ovarian cancer. SPIE Newsroom.Conference paper Vo-Dinh, T., Mahadevan-Jansen, A., Grundfest, W. S., Desroches, J., Pichette, J., Goyette, A., Tremblay, M.-A., Jermyn, M., Petrecca, K., & Leblond, F. (2016, February). Multimodal optical biopsy probe to improve the safety and diagnostic yield of brain needle biopsies [Paper]. Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV, part of Photonics West 2016, San Francisco, California, USA.Conference paper Jermyn, M., Desroches, J., Mercier, J., St-Arnaud, K., Guiot, M. C., Petrecca, K., & Leblond, F. (2016, February). Neural networks improve brain cancer detection with Raman spectroscopy in the presence of light artifacts [Paper]. Clinical and Translational Neurophotonics; Neural Imaging and Sensing; and Optogenetics and Optical Manipulation, USA (6 pages).Journal article Jermyn, M., Desroches, J., Mercier, J., Tremblay, M.-A., St-Arnaud, K., Guiot, M.-C., Petrecca, K., & Leblond, F. (2016). Neural networks improve brain cancer detection with Raman spectroscopy in the presence of operating room light artifacts. Journal of Biomedical Optics, 21(9).Journal article Jermyn, M., Desroches, J., Mercier, J., St-Arnaud, K., Guiot, M.-C., Leblond, F., & Petrecca, K. (2016). Raman spectroscopy detects distant invasive brain cancer cells centimeters beyond MRI capability in humans. Biomedical Optics Express, 7(12), 5129-5137.Conference paper Choi, B., Kollias, N., Zeng, H., Kang, H. W., Wong, B. J. F., Ilgner, J. F., Tearney, G. J., Gregory, K. W., Marcu, L., Skala, M. C., Campagnola, P. J., Mandelis, A., Morris, M. D., St-Georges-Robillard, A., Masse, M., Kendall-Dupont, J., Strupler, M., Patra, B., Jermyn, M., ... Gervais, T. (2016, February). Spectroscopic imaging system for high-throughput viability assessment of ovarian spheroids or microdissected tumor tissues (MDTs) in a microfluidic chip [Paper]. Photonic Therapeutics and Diagnostics XII, San Francisco, California.Journal article St-Arnaud, K., Aubertin, K., Strupler, M., Jermyn, M., Petrecca, K., Trudel, D., & Leblond, F. (2016). Wide-field spontaneous Raman spectroscopy imaging system for biological tissue interrogation. Optics Letters, 41(20), 4692-4695.
- 2015 (14)
Journal article Desroches, J., Jermyn, M., Mok, K., Lemieux-Leduc, C., Mercier, J., St-Arnaud, K., Urmey, K., Guiot, M.-C., Marple, E., Petrecca, K., & Leblond, F. (2015). Characterization of a Raman spectroscopy probe system for intraoperative brain tissue classification. Biomedical Optics Express, 6(7), 2380-2397.Conference paper Pichette, J., Goyette, A., Soulez, G., Wilson, B., & Leblond, F. (2015, April). Development of a multispectral monte carlo simulation technique for blood vessels detection during brain needle biopsy procedures [Paper]. Optics and the Brain (BRAIN 2015), Vancouver, Canada.Journal article Jermyn, M., Gosselin, Y., Valdés, P. A., Sibai, M., Kolste, K., Mercier, J., Angulo, L., Roberts, D. W., Paulsen, K. D., Petrecca, K., Daigle, O., Wilson, B. C., & Leblond, F. (2015). Improved sensitivity to fluorescence for cancer detection in wide-field image-guided neurosurgery. Biomedical Optics Express, 6(12), 5063-5074.Journal article Jermyn, M., Mok, K., Mercier, J., Desroches, J., Pichette, J., Saint-Arnaud, K., Bernstein, L., Guiot, M. C., Petrecca, K., & Leblond, F. (2015). Intraoperative brain cancer detection with Raman spectroscopy in humans. Science Translational Medicine, 7(274), 9-9.Journal article Leblond, F., Jermyn, M., Mok, K., Mercier, J., Desroches, J., Pichette, J., Saint-Arnaud, K., Guiot, M.-C., & Petrecca, K. (2015). Intraoperative detection of cancerous brain tissue using Raman spectroscopy. SPIE Newsroom.Conference paper Jermyn, M., Mok, K., Mercier, J., Desroches, J., Pichette, J., Saint-Arnaud, K., Guiot, M. C., Petrecca, K., & Leblond, F. (2015, February). Intraoperative detection of glioma invasion beyond MRI enhancement with Raman spectroscopy in humans [Paper]. SPIE Conference on Optical Biopsy XIII: Toward Real-Time Spectroscopic Imaging and Diagnosis, San Francisco, California (6 pages).Journal article Jermyn, M., Kolste, K., Pichette, J., Sheehy, G., Angulo-Rodriguez, L., Paulsen, K. D., Roberts, D. W., Wilson, B. C., Petrecca, K., & Leblond, F. (2015). Macroscopic-imaging technique for subsurface quantification of near-infrared markers during surgery. Journal of Biomedical Optics, 20(3).Journal article Kolste, K. K., Kanick, S. C., Valdés, P. A., Jermyn, M., Wilson, B. C., Roberts, D. W., Paulsen, K. D., & Leblond, F. (2015). Macroscopic optical imaging technique for wide-field estimation of fluorescence depth in optically turbid media for application in brain tumor surgical guidance. Journal of Biomedical Optics, 20(2), 026002 (8 pages).Conference paper Sibai, M., Veilleux, I., Elliott, J. T., Leblond, F., Roberts, D. W., & Wilson, B. C. (2015, February). Quantitative fluorescence imaging enabled by spatial frequency domain optical-property mapping in the sub-diffusive regime for surgical guidance [Paper]. SPIE Conference on Molecular-Guided Surgery: Molecules, Devices, and Applications, San Francisco, California.Journal article Valdés, P. A., Jacobs, V., Harris, B. T., Wilson, B. C., Leblond, F., Paulsen, K. D., & Roberts, D. W. (2015). Quantitative fluorescence using 5-aminolevulinic acid-induced protoporphyrin IX biomarker as a surgical adjunct in low-grade glioma surgery. Journal of Neurosurgery, 123(3), 771-780.Journal article Sibai, M., Veilleux, I., Elliott, J. T., Leblond, F., & Wilson, B. C. (2015). Quantitative spatial frequency fluorescence imaging in the sub-diffusive domain for image-guided glioma resection. Biomedical Optics Express, 6(12), 4923-4933.Journal article Pichette, J., Goyette, A., Picot, F., Tremblay, M.-A., Soulez, G., Wilson, B. C., & Leblond, F. (2015). Sensitivity analysis aimed at blood vessels detection using interstitial optical tomography during brain needle biopsy procedures. Biomedical Optics Express, 6(11), 4238-4254.Journal article Goyette, A., Pichette, J., Tremblay, M.-A., Laurence, A., Jermyn, M., Mok, K., Paulsen, K. D., Roberts, D. W., Petrecca, K., Wilson, B. C., & Leblond, F. (2015). Sub-diffuse interstitial optical tomography to improve the safety of brain needle biopsies: a proof-of-concept study. Optics Letters, 40(2), 170-173.Conference paper Desroches, J., Goyette, A., Pichette, J., Jermyn, M., Mok, K., Mercier, J., Saint-Arnaud, K., Guiot, M.-C., Petrecca, K., Wilson, B. C., & Leblond, F. (2015, April). Towards the combined use of Raman spectroscopy and interstitial optical tomography to improve the safety and diagnostic accuracy of brain needle biopsies [Paper]. Optics and the Brain, part of Optics in the Life Sciences (BRAIN 2015), Vancouver, Canada.
- 2014 (5)
Journal article Valdés, P. A., Bekelis, K., Harris, B. T., Wilson, B. C., Leblond, F., Kim, A., Simmons, N. E., Erkmen, K., Paulsen, K. D., & Roberts, D. W. (2014). 5-Aminolevulinic Acid-Induced Protoporphyrin IX Fluorescence in Meningioma: Qualitative and Quantitative Measurements In Vivo. Neurosurgery, 10(1), 74-82.Conference paper Jermyn, M., Mok, K., Desroches, J., Mercier, J., Saint-Arnaud, K., Bernstein, L., Guiot, M.-C., Petrecca, K., & Leblond, F. (2014, April). Brain Tumor Resection Guided with Single-Point Raman Spectroscopy: In-Human Results [Paper]. Biomedical Optics 2014, Miami, Florida, USA. Published in Biomedical optics.Conference paper Beaulieu-Ouellet, E., Bélanger, S., Deterre, R., Gariépy, C., De Montigny, É., Leblond, F., Boudoux, C., & Lesage, F. (2014, February). Conference 8928A: Optical Techniques in Neurosurgery, Brain Imaging, and Neurobiology [Paper]. 2014 Photonics West, San Francisco, California.Conference paper Aubertin, K., Trinh, V., Jermyn, M., Desroches, J., St-Pierre, C., Vladoiu, M.-C., Grosset, A.-A., Saad, F., Trudel, D., & Leblond, F. (2014, February). Raman Spectroscopy for Prostate Cancer Detection and Characterization [Paper]. 58th Annual Meeting of the Biophysical-Society, San Francisco, CA. Published in Biophysical Journal, 112(3).Journal article Thouin, F., Leblond, F., Martel, R., Verhaegen, M., & Daigle, O. (2014). Ultra Fast Raman Hyperspectral Imaging using Bragg Tunable Filters and a High Performance Emccd Camera. Biophysical Journal, 106(2), 613A-613A.
- 2013 (5)
Conference paper Tichauer, K. M., Holt, R. W., Leblond, F., & Pogue, B. W. (2013, February). An overview of time-domain diffuse fluorescence imaging: Instrumentation and applications [Paper]. Optical Tomography and Spectroscopy of Tissue X, San Francisco, CA, United states.Journal article Tichauer, K. M., Holt, R. W., El-Ghussein, F., Davis, S. C., Samkoe, K. S., Gunn, J. R., Leblond, F., & Pogue, B. W. (2013). Dual-tracer background subtraction approach for fluorescent molecular tomography. Journal of Biomedical Optics, 18(1), 16003.Journal article Holt, R. W., Leblond, F., & Pogue, B. W. (2013). Methodology to Optimize Detector Geometry in Fluorescence Tomography of Tissue Using the Minimized Curvature of the Summed Diffuse Sensitivity Projections. Journal of the Optical Society of America A: Optics Image Science and Vision, 30(8), 1613-1619.Conference paper Holt, R. W., Tichauer, K. M., El-Ghussein, F., Gunn, J. R., Leblond, F., & Pogue, B. W. (2013, February). Optimized methodology for low-contrast fluorescence recovery using a new approach for reference tracer normalization [Paper]. Optical Tomography and Spectroscopy of Tissue X, San Francisco, CA, United states.Conference paper Holt, R. W., Leblond, F., & Pogue, B. W. (2013, February). Toward ideal imaging geometry for recovery independence in fluorescence molecular tomography [Paper]. Multimodal Biomedical Imaging VIII, San Francisco, CA, United states.
- 2012 (10)
Journal article Roberts, D. W., Valdés, P. A., Harris, B. T., Hartov, A., Fan, X., Ji, S., Pogue, B. W., Leblond, F., Tosteson, T. D., Wilson, B. C., & Paulsen, K. D. (2012). Adjuncts for maximizing resection: 5-aminolevuinic acid. Clinical Neurosurgery, 59(Supplement), 75-78.Journal article Valdés, P. A., Leblond, F., Kim, A., Wilson, B. C., Paulsen, K. D., & Roberts, D. W. (2012). A spectrally-constrained dual-band normalization technique for protoporphyrin IX quantification in fluorescence-guided surgery. Optics Letters, 37(11), 1817-1819.Journal article Basevi, H. R. A., Tichauer, K. M., Leblond, F., Pogue, B. W., Dehghani, H., Guggenheim, J. A., Holt, R. W., & Styles, I. B. (2012). Compressive sensing based reconstruction in bioluminescence tomography improves image resolution and robustness to noise. Biomedical Optics Express, 3(9), 2131-2141.Journal article Tichauer, K. M., Holt, R. W., Samkoe, K. S., El-Ghussein, F., Gunn, J. R., Jermyn, M., Dehghani, H., Leblond, F., & Pogue, B. W. (2012). Computed tomography-guided time-domain diffuse fluorescence tomography in small animals for localization of cancer biomarkers. Journal of Visualized Experiments (65), e4050.Journal article Roberts, D. W., Valdés, P. A., Harris, B. T., Hartov, A., Fan, X., Ji, S., Leblond, F., Tosteson, T. D., Wilson, B. C., & Paulsen, K. D. (2012). Glioblastoma multiform treatment with clinical trials for surgical resection (aminolevulinic acid). Neurosurgery Clinics of North America, 23(3), 371-377.Journal article Bonfert-Taylor, P., Leblond, F., Holt, R. W., Tichauer, K. M., Pogue, B. W., & Taylor, E. C. (2012). Information loss and reconstruction in diffuse fluorescence tomography. Journal of the Optical Society of America A: Optics Image Science and Vision, 29(3), 321-330.Journal article Valdés, P. A., Leblond, F., Jacobs, V. L., Paulsen, K. D., & Roberts, D. W. (2012). In vivo Fluorescence Detection in Surgery: A Review of Principles, Methods, and Clinical Applications. Current Medical Imaging Reviews, 8(3), 211-232.Journal article Holt, R. W., Tichauer, K. M., Zhu, Q., Dehghani, H., Pogue, B. W., & Leblond, F. (2012). Multiple-gate time domain diffuse fluorescence tomography allows more sparse tissue sampling without compromising image quality. Optics Letters, 37(13), 2559-2561.Journal article Valdés, P. A., Leblond, F., Jacobs, V. L., Wilson, B. C., Paulsen, K. D., & Roberts, D. W. (2012). Quantitative, spectrally-resolved intraoperative fluorescence imaging. Scientific Reports, 2(1), 798.Journal article Konecky, S. D., Owen, C. M., Rice, T., Valdes, P. A., Kolste, K., Wilson, B. C., Leblond, F., Roberts, D. W., Paulsen, K. D., & Tromberg, B. J. (2012). Spatial frequency domain tomography of protoporphyrin IX fluorescence in preclinical glioma models. Journal of Biomedical Optics, 17.